Welcome to mutty Professor
This film menetion a Genetics professor Sherman Klump weighs in at 400 pounds and needs the help of his large, eccentric family to flight off his Slimmed-down alterego,"Buddy Love." He is a kind, considerate, and a genuinely nice guy. Sherman is also appallingly overweight; coupled with the fact that he's painfully shy and a bit clumsy, his romantic prospects are rather bleak. When Sherman finds himself working with a pretty graduate student, Carla Purty (Jada Pinkett), he falls in love and is eager to impress her, but at an upscale nightclub, his weight attracts the attention of an insult comic (Dave Chappelle) and his bumbling spoils the evening. Sherman's latest project is a genetic weight loss formula, and despondent over his failure to win Carla's heart, he subjects himself to a massive dose. Will Sherman transformed himself into a slim, trim, and handsome Buddy Love???

http://www.starpulse.com/movie/The_Nutty_Professor/V136219/0/2/
http://www.amazon.com/The-Nutty-Professor/dp/B001K3GASM
http://www.imdb.com/title/tt0117218/